Electrostatic Free Energy Landscapes for DNA Helix Bending
نویسندگان
چکیده
منابع مشابه
Electrostatic free energy landscapes for DNA helix bending.
Nucleic acids are highly charged polyanionic molecules; thus, the ionic conditions are crucial for nucleic acid structural changes such as bending. We use the tightly bound ion theory, which explicitly accounts for the correlation and ensemble effects for counterions, to calculate the electrostatic free energy landscapes for DNA helix bending. The electrostatic free energy landscapes show that ...
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The DNA helices are taken as the canonical B-form and are produced from the previously developed grooved primitive model [1]. The grooved primitive model retains a high degree of realistic helical structure and phosphate charge distribution of DNA [2], and is tractable for analytical statistical mechanical theories [3]-[5]. We use the B-form DNA helix since it is the most common and stable form...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2008
ISSN: 0006-3495
DOI: 10.1529/biophysj.107.122366